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What is the role of hydroxyurea in sickle cell disease? Hydroxyurea, a myelosuppressive agent, is the only effective drug proven to reduce the frequency of painful episodes. It raises the level of HbF and the haemoglobin level. It usually decreases the rate of painful episodes by 50 %. It was first tested in sickle cell disease in 1984.
How is essential thrombocytosis treated? Low-dose aspirin therapy (eg, ≤100 mg/day) is acceptable if the ristocetin cofactor level is at least 30% in absence of other high risk factors; if it is less than 30%, all aspirin should be avoided. Hydroxyurea is generally considered the first-line drug for cytoreductive therapy in essential thrombocytosis.
Do tumors hurt? The feel of a breast lump depends on its cause, location, and growth. They can vary greatly from painful, hard, and immobile to soft, painless, and easily moveable. According to, lumps are most likely to be cancerous if they do not cause pain, are hard, unevenly shaped, and immobile.
Do cancer patients know when they are dying? When death is very near, you might notice some physical changes such as changes in breathing, loss of bladder and bowel control and unconsciousness. It can be emotionally very difficult to watch someone go through these physical changes. But they are part of a natural dying process.
What types of cancer screenings are available? Screening tests that have not been shown to be effective may still be offered, especially to people who are known to be at increased risk of cancer. Alpha-fetoprotein blood test. Breast MRI. CA-125 test. Clinical breast exams and regular breast self-exams. PSA test. Skin exams. Transvaginal ultrasound. Virtual colonoscopy.
Does chemo cause metastasis? Tumors backfire on chemotherapy. Summary: Chemotherapy is an effective treatment for breast cancer, yet some patients develop metastasis in spite of it. Researchers have now discovered that chemotherapy -treated mammary tumors produce small vesicles that may help them spread to other organs.
What are chemo pills used for? Oral chemotherapy (chemo) is medicine used to shrink a tumor or kill cancer cells. Oral chemo is usually taken at home as a pill or liquid.
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